Contemporary off a 13-3 season and a visit to the AFC Championship Sport, the Buffalo Payments can be examined to start out the 2021 NFL schedule as they host the Pittsburgh Steelers. That is one among 5 video games between playoff groups from a season in the past, and the Payments are 6.5-point favorites within the Week 1 NFL odds from Caesars Sportsbook. Solely the Rams and 49ers are greater favorites, with the Week 1 strains exhibiting Los Angeles favored by 7.5 over Chicago and San Francisco favored by 8.5 over Detroit.
Along with the 5 matchups between playoff groups, there are two divisional matchups, with the Jaguars favored by three over the Texans and the Patriots favored by a discipline aim over the Dolphins within the Week 1 NFL spreads. Which manner must you lean on all 15 remaining video games as you make your Week 1 NFL bets? The entire Week 1 NFL strains are listed beneath, and SportsLine’s superior laptop mannequin has all of the NFL betting recommendation and predictions it is advisable make one of the best Week 1 NFL picks now.
The mannequin, which simulates each NFL recreation 10,000 occasions, is up nearly $7,900 for $100 gamers on top-rated NFL picks since its inception six years in the past. It went a scorching 24-14 on top-rated NFL picks final season, returning greater than $800. The mannequin additionally enters the 2021 season on an unimaginable 120-78 run on top-rated NFL picks that dates again to the 2017 season.
The mannequin additionally ranked within the Prime 10 on NFLPickWatch 4 of the previous 5 years on straight-up NFL picks and beat greater than 94 p.c of CBS Sports activities Soccer Choose’em gamers 4 occasions throughout that span. Anybody who has adopted it’s manner up.
Prime Week 1 NFL predictions
One of many high Week 1 NFL predictions the mannequin recommends: The 49ers (-8.5) cowl the unfold in opposition to the Lions. The 49ers have been top-of-the-line street groups within the NFL, successful seven of their eight regular-season street video games on their solution to changing into NFC Champions two seasons in the past and capturing 5 of their six total wins on the street final yr.
In the meantime, the Lions solely received as soon as at residence final season and Dan Campbell has been tasked with one other tough rebuild. The Lions completed twentieth in scoring and complete offense final season and changed quarterback Matthew Stafford with Jared Goff. In addition they let broad receiver Kenny Golladay stroll in free company. That is going to place a variety of strain on a protection that ranked final in factors allowed and yards allowed a season in the past.
The mannequin is anticipating a wholesome 49ers offense to pile up over 450 yards of complete offense. The road has been shifting in direction of San Francisco after opening at 7.5 factors, however the guests nonetheless cowl in over 50 p.c of SportsLine’s simulations.
One other one of many high Week 1 NFL picks from the mannequin: The Panthers (-4) cowl as residence favorites in opposition to the Jets. After being chosen by the Jets with the No. 3 total within the 2018 NFL Draft and being traded away after simply three seasons, Darnold will get an instantaneous probability at revenge with the Jets coming to go to him in his new residence in Charlotte.
Darnold has regarded comfy within the preseason and is surrounded by far and away essentially the most gifted group of ability gamers he is ever had. Christian McCaffrey is wholesome after lacking 13 video games a season in the past and may take the strain off Darnold by powering a stable working recreation whereas additionally being arguably one of the priceless receivers within the recreation too. The mannequin predicts that McCaffrey piles up over 130 yards of complete offense to assist the Panthers cowl in effectively over 50 p.c of simulations.
The way to make Week 1 NFL picks
The mannequin has additionally made the decision on who wins and covers in each different recreation on the Week 1 NFL schedule, and it is calling for a Tremendous Bowl contender to go down onerous. You possibly can solely get each choose for each recreation at SportsLine.
So what NFL picks are you able to make with confidence? And which Tremendous Bowl contender goes down onerous? Take a look at the most recent NFL odds beneath, then go to SportsLine to see which groups win and canopy the unfold, all from a confirmed laptop mannequin that has returned nearly $7,900 since its inception, and discover out.
Week 1 NFL odds (by way of Caesars)
Sunday, Sept. 12
Featured Sport | Buffalo Payments vs. Pittsburgh Steelers
Jets at Panthers (-4, 44.5)
Featured Sport | Carolina Panthers vs. New York Jets
Featured Sport | Houston Texans vs. Jacksonville Jaguars
Featured Sport | Tennessee Titans vs. Arizona Cardinals
Chargers at Washington (-1, 44.5)
Featured Sport | Washington Soccer Group vs. Los Angeles Chargers
Featured Sport | Atlanta Falcons vs. Philadelphia Eagles
Featured Sport | Indianapolis Colts vs. Seattle Seahawks
Featured Sport | Cincinnati Bengals vs. Minnesota Vikings
49ers at Lions (+8.5, 46)
Featured Sport | Detroit Lions vs. San Francisco 49ers
Featured Sport | Kansas Metropolis Chiefs vs. Cleveland Browns
Featured Sport | New England Patriots vs. Miami Dolphins
Featured Sport | New York Giants vs. Denver Broncos
Featured Sport | New Orleans Saints vs. Inexperienced Bay Packers
Featured Sport | Los Angeles Rams vs. Chicago Bears
Monday, Sept. 13
Featured Sport | Las Vegas Raiders vs. Baltimore Ravens